La Salle College first organised exchange programmes and provided international learning experiences outside the classroom in 1996. With the rapid expansion of exchange activities, the La Salle College Exchange Team was established in 2012.

Over the past two decades, La Salle College has established partnerships with various schools all over the world, including: Mainland China, Singapore, Australia, New Zealand, France, Spain, the Netherlands, and Argentina.

Various outbound programmes with different themes have been organised to broaden students' horizons, enhance their understanding of the rapidly changing world, and equip them with self-management competence, which are indisputable skills needed among 21st-century learners.